Talking about like shows to see? Clubs? Music? or just anything?
I live in Vegas and I personally hate the strip, clubs, and pools and shit.
I recommend going downtown LV by Freemont, it's starting to come together with a lot of really good bars.
CommonWealth, The Griffin, Beauty Bar, Downtown Cocktail Room, Atomic, Gold Spike.
(Except "Insert Coin(s)", that bar is full of a dudes playing arcade games)
Only clubs I recommend is Surrender, or Marquee. Those usually have the least amount of mohawk, Affliction shirt wearing, tribal sleeve douche bags.
As far as shows, any Cirque show is good. Zumanity was my favorite (I still need to see Beatles Love)