Blaypbs is pretty on point. Harpoon Brewery tour if you like better beer. Check out Fenway, you can get tickets from the scalpers on the Brookline Ave bridge at the top of Lansdowne, tickets get cheaper if you want to miss the first couple innings. Check out the North End for some italian food and from there you can walk over to Fanuiel Hall/Quincy Market/Financial district for a shitload of clubs and bars. Public transportation sucks dick here, last train is 1230 and last call is 145ish, plan accordingly. We also have the Museum of Science, Museam of Fine Arts, and an aquarium. The Institute of Contemporary Art is on the waterfront which is really nice, some restaurants there as well. Newbury street is where all the rich people go. Tons of shops, tons of restaurants, beautiful women and ridiculous cars. Worth checking out while you're here. Freedom trail is quick and easy and you get to walk around the city http://en.wikipedia.org/wiki/Freedom_Trail. Public Garden and the arboretum for more outdoors stuff. That's all I can think of at the moment.