lord_casek Posted June 29, 2007 Share Posted June 29, 2007 Potential cure for HIV discovered http://news.yahoo.com/s/afp/20070628/hl_afp/usgermanyhealth;_ylt=AvV3uZHh5CyPZZkjs3UPh6Ba24cA by Mira Oberman Thu Jun 28, 2:39 PM ET CHICAGO (AFP) - In a breakthrough that could potentially lead to a cure for HIV infection, scientists have discovered a way to remove the virus from infected cells, a study released Thursday said. The scientists engineered an enzyme which attacks the DNA of the HIV virus and cuts it out of the infected cell, according to the study published in Science magazine. The enzyme is still far from being ready to use as a treatment, the authors warned, but it offers a glimmer of hope for the more than 40 million people infected worldwide. "A customized enzyme that effectively excises integrated HIV-1 from infected cells in vitro might one day help to eradicate (the) virus from AIDS patients," Alan Engelman, of Harvard University's Dana-Farber Cancer Institute, wrote in an article accompanying the study. Current treatments focus on suppressing the HIV virus in order to delay the onset of AIDS and dramatically extend the life of infected patients. What makes HIV so deadly, however, is its ability to insert itself into the body's cells and force those cells to produce new infection. "Consequently the virus becomes inextricably linked to the host, making it virtually impossible to 'cure' AIDS patients of their HIV-1 infection," Engelman explained. That could change if the enzyme developed by a group of German scientists can be made safe to use on people. That enzyme was able to eliminate the HIV virus from infected human cells in about three months in the laboratory. The researchers engineered an enzyme called Tre which removes the virus from the genome of infected cells by recognizing and then recombining the structure of the virus's DNA. This ability to recognize HIV's DNA might one day help overcome one of the biggest obstacles to finding a cure: the ability of the HIV virus to avoid detection by reverting to a resting state within infected cells which then cease to produce the virus for months or even years. "Numerous attempts have been made to activate these cells, with the hope that such strategies would sensitize the accompanying viruses to antiviral drugs, leading to virus eradication," Engelman wrote. "Advances with such approaches in patients have been slow to materialize." New experiments must be designed to see if the Tre enzyme can be used to recognize these dormant infected cells, he wrote. "Although favorable results would represent perhaps only a baby step toward eventual use in patients, the discovery of the Tre recombinase proves that enzymatic removal of integrated HIV-1 from human chromosomes is a current-day reality," he said. The researchers who developed the enzyme were optimistic about their ability to design additional enzymes which would target other parts of the virus's DNA. However they warned that there were significant barriers to overcome before the enzyme could be used to help cure patients. "The most important, and likely most difficult, among these is that the enzyme would need efficient and safe means of delivery and would have to be able to function without adverse side effects," wrote lead author Indrani Sarkar of the Max Planck Institute for Molecular Cell Biology and Genetics in Dresden. "Nevertheless the results we present offer an early proof of principal for this type of approach, which we speculate might form a useful basis for the development of future HIV therapies," Sarkar concluded. PWNDED NEWB Quote Link to comment Share on other sites More sharing options...
IrishCarBombs Posted June 29, 2007 Share Posted June 29, 2007 YAYYYYYY!!!!!!!!! i can stop fucking just stuff animals now!!!!! Quote Link to comment Share on other sites More sharing options...
MAR Posted June 29, 2007 Share Posted June 29, 2007 woah. ground breaking. Quote Link to comment Share on other sites More sharing options...
GEEB Posted June 29, 2007 Share Posted June 29, 2007 Im immuned to all known strains of the HIV infection, the doctors and the military wanted to test me but i was like "no way, your not gunna touch my cock n ballz." Quote Link to comment Share on other sites More sharing options...
lord_casek Posted June 29, 2007 Author Share Posted June 29, 2007 Im immuned to all known strains of the HIV infection, the doctors and the military wanted to test me but i was like "no way, your not gunna touch my cock n ballz." was it the navy? Quote Link to comment Share on other sites More sharing options...
Hayabusa Posted June 30, 2007 Share Posted June 30, 2007 im immune too u cant catch that shit twice so just get it now, and ur mind is free of stress later Quote Link to comment Share on other sites More sharing options...
iloveboxcars Posted June 30, 2007 Share Posted June 30, 2007 sweet, now i dont have to worry about condoms. Quote Link to comment Share on other sites More sharing options...
alure Posted June 30, 2007 Share Posted June 30, 2007 thats crazy. Quote Link to comment Share on other sites More sharing options...
Avancier2 Posted June 30, 2007 Share Posted June 30, 2007 if this shit becomes a reality I am never buying condoms again. ever. Quote Link to comment Share on other sites More sharing options...
tutleone Posted June 30, 2007 Share Posted June 30, 2007 Arent you forgetting about teh Clap and Crabz + teh h3rp3s? Quote Link to comment Share on other sites More sharing options...
Qawee Posted June 30, 2007 Share Posted June 30, 2007 who cares about that shit? DIDNT YOU HEAR THE MAN?!? NO AIDS!!! Quote Link to comment Share on other sites More sharing options...
Theo Huxtable. Posted June 30, 2007 Share Posted June 30, 2007 I was told by a professor that 4% of all white people cannot contract HIV. Scientists theorize that this strong immune system is a result of the numerous waves of "Black Plague" pandemics that swept Europe several centuries ago. Quote Link to comment Share on other sites More sharing options...
Theo Huxtable. Posted June 30, 2007 Share Posted June 30, 2007 "hell yeah, i guess that means i'm back to playin' bassitbawl!" Quote Link to comment Share on other sites More sharing options...
Mauler5150 Posted June 30, 2007 Share Posted June 30, 2007 Damn, is this for real?? Magic Johnson is going to come back?? Quote Link to comment Share on other sites More sharing options...
SADDAM HUSSEIN Posted June 30, 2007 Share Posted June 30, 2007 i thought they found the cure for hiv already Quote Link to comment Share on other sites More sharing options...
GEEB Posted June 30, 2007 Share Posted June 30, 2007 shhhh! Quote Link to comment Share on other sites More sharing options...
defyoner Posted June 30, 2007 Share Posted June 30, 2007 i cannot read that much. i need the cliff notes. Quote Link to comment Share on other sites More sharing options...
Hayabusa Posted June 30, 2007 Share Posted June 30, 2007 i cannot read that much. i need the cliff notes. they found a cure for aids possibly Quote Link to comment Share on other sites More sharing options...
SADDAM HUSSEIN Posted June 30, 2007 Share Posted June 30, 2007 this will be the 4th time i've heard of the cure for aids in 2 years Quote Link to comment Share on other sites More sharing options...
BrineShrimpr Posted June 30, 2007 Share Posted June 30, 2007 Unbelievable Quote Link to comment Share on other sites More sharing options...
Avancier2 Posted June 30, 2007 Share Posted June 30, 2007 this will be the 4th time i've heard of the cure for aids in 2 years killjoy. Quote Link to comment Share on other sites More sharing options...
lepthebeard Posted June 30, 2007 Share Posted June 30, 2007 ...you cats got it all wrong............... Quote Link to comment Share on other sites More sharing options...
BruceLeroy Posted June 30, 2007 Share Posted June 30, 2007 craziness Quote Link to comment Share on other sites More sharing options...
IrishCarBombs Posted June 30, 2007 Share Posted June 30, 2007 "hell yeah, i guess that means i'm back to playin' bassitbawl!" bwahahaha Quote Link to comment Share on other sites More sharing options...
*PROTOCOL* Posted June 30, 2007 Share Posted June 30, 2007 I heard they cant find a trace of HIV in Magic Johnson. Quote Link to comment Share on other sites More sharing options...
IrishCarBombs Posted June 30, 2007 Share Posted June 30, 2007 cause he has aids Quote Link to comment Share on other sites More sharing options...
AyeBee Posted June 30, 2007 Share Posted June 30, 2007 Magic Johnson has had the cure for ages Quote Link to comment Share on other sites More sharing options...
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