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Discussion in 'Channel Zero' started by High Priest, Dec 9, 2004.

  1. High Priest

    High Priest Elite Member

    Joined: Jan 1, 2002 Messages: 4,928 Likes Received: 4
    Im putting this thread together because i honestly know very little about Down Syndrome and felt like doing a little research into the subject to try and learn a little more about the condition.So anyway, here's what i found if anyone has any interest .

    Cause: Down syndrome is usually caused by an error in cell division called non-disjunction. However, two other types of chromosomal abnormalities, mosaicism and translocation, are also implicated in Down syndrome - although to a much lesser extent. Regardless of the type of Down syndrome which a person may have, all people with Down syndrome have an extra, critical portion of the number 21 chromosome present in all, or some, of their cells. This additional genetic material alters the course of development and causes the characteristics associated with the syndrome.

    Why should we be concerned about Down syndrome?

    Chromosomal abnormalities are a widespread medical problem, with Down syndrome being the most common genetic condition. One in every 800 to 1,000 children is born with Down syndrome.

    More than 50 percent of miscarriages are caused by a chromosomal abnormality. As many as 25 percent of all miscarriages are caused by a trisomy, which is the presence of three copies of a particular chromosome, rather than the normal two.

    The most common form of Down syndrome is called Trisomy 21, because it involves an extra copy of the 21st chromosome. Twenty to 25 percent of children conceived with Down syndrome survive past birth.

    Is Down syndrome transmitted from the mother or father?

    The additional genetic material which causes Down syndrome can originate from either the father or the mother. Approximately five percent of the cases have been traced to the father.

    Who has the highest risk of having a child with Down syndrome?

    Down syndrome affects people of all races and economic levels. Women age 35 and older have a significantly increased risk of having a child with Down syndrome. A 35-year-old woman has a one in 400 chance of conceiving a child with Down syndrome and this chance increases gradually to one in 110 by age 40. At age 45 the incidence becomes approximately one in 35.

    Since many couples are postponing parenting until later in life, the incidence of Down syndrome conceptions is expected to increase. Therefore, genetic counseling for parents is becoming increasingly important. Still, many physicians are not fully informed about advising their patients about the of incidence of Down syndrome, advancements in diagnosis and the protocols for care and treatment of babies born with Down syndrome.

    *Alright, here's something interesting :

    In June 2001, a study was published by the Center for Disease Control and Prevention indicating a stark racial disparity in the median life spans of people with Down syndrome. The study, based on an analysis of 34,000 multiple-cause mortality files from 1968 to 1997, indicated that the median age at death for white people with Down syndrome is 50 years, while it is 25 years for black people and 11 years for people of other races.

    Although NDSS has operated on the assumption that a level of socio-economic disparity exists (due to poor health care, access to information and other factors), and has worked in a variety of ways to address it, the Society was dismayed to learn that the racial disparity is so stark.

    The Society reinforces the study's assertion that there is no evidence indicating that people with Down syndrome who are black or of other races are more likely to develop life-threatening conditions associated with Down syndrome.

    By working through a national network of parent support groups and a new health care professional program, NDSS has tried to address the larger issues of education (both professional and parental), community support and access to quality medical care. It is clear that more needs to be done that is specifically targeted to those who are black and of other races.

    This issue is of utmost importance to the Society and we are already working on ways to address it. Further study to determine the causes of this disparity are critical. By determining the causes, NDSS can then be better equipped to address them and reduce this tragic disparity.

    Myth's & Truth's:
    Myth: Down syndrome is a rare genetic disorder.

    Truth: Down syndrome is the most commonly occurring genetic condition. One in every 800 to 1,000 live births is a child with Down syndrome, representing approximately 5,000 births per year in the United States alone. Today, Down syndrome affects more than 350,000 people in the United States.

    Myth: Most children with Down syndrome are born to older parents.

    Truth: Eighty percent of children born with Down syndrome are born to women younger than 35-years-old. However, the incidence of births of children with Down syndrome increases with the age of the mother.

    Myth: People with Down syndrome are severely retarded.

    Truth: Most people with Down syndrome have IQs that fall in the mild to moderate range of retardation. Children with Down syndrome are definitely educable and educators and researchers are still discovering the full educational potential of people with Down syndrome.

    Myth: Down syndrome can never be cured.

    Truth: Research on Down syndrome is making great strides in identifying the genes on chromosome 21 that cause the characteristics of Down syndrome. Scientists now feel strongly that it will be possible to improve, correct or prevent many of the problems associated with Down syndrome in the future.
  2. Herbivore

    Herbivore Senior Member

    Joined: Oct 12, 2004 Messages: 1,431 Likes Received: 1
    interesting.... especially the race-related findings.
  3. Rodney Trotter

    Rodney Trotter Senior Member

    Joined: Aug 23, 2001 Messages: 1,683 Likes Received: 1

    Now where's that god damn flick?
  4. GnomeToys

    GnomeToys Elite Member

    Joined: Jun 24, 2003 Messages: 2,616 Likes Received: 4


  5. imported_YEAHMANWORD

    imported_YEAHMANWORD Member

    Joined: Jul 9, 2001 Messages: 985 Likes Received: 0
  6. MOOGLE?

    MOOGLE? 12oz Loyalist

    Joined: May 23, 2000 Messages: 11,495 Likes Received: 502
    the last picture of the little girl with the spoon is cute.

    i have a cousin with down syndrome..and she is turning 34 next june..

    i dont have much else to add to this thread..
  7. Dick Quickwood

    Dick Quickwood 12oz Loyalist

    Joined: Aug 25, 2002 Messages: 14,783 Likes Received: 14
    fascinating, i was born when my mom was 34 or 35, my brother, 39
  8. duct

    duct New Jack

    Joined: Nov 3, 2004 Messages: 87 Likes Received: 0
    it is a shame for these young people but theres not really alot for us to be able to do about it and yes it is facinating about that race related bit up top and did u know if ur kind and caring to people with down syndrome and treat them with the utter respect that every one gets who u know they can bond with u like glue and its amazing cus they can be such loving people just like the rest of us and thats what poeple forget there HUMAN BEINGS ASWELL so dont try to rip the piss out of them cus they maywell look and seem different but the actually are safe happy loving carring people just like ur selfs
  9. Nekro

    Nekro Elite Member

    Joined: Feb 19, 2003 Messages: 2,568 Likes Received: 1
    There are a few down syndrome kids at my school. I sort of grew up around them due to the whole "mainstreaming" thing, and I have gym with 'em.
  10. dirtyhoodrat

    dirtyhoodrat Junior Member

    Joined: Oct 11, 2004 Messages: 138 Likes Received: 0
    One in every 800 to 1,000 children is born with Down syndrome.>>

    that is crazy i had no idea it was so many.. pretty interesting
  11. CinchedWaist

    CinchedWaist Elite Member

    Joined: Sep 11, 2003 Messages: 2,691 Likes Received: 1
    Chimpanzees also can get downs syndrome.
    goes to show how closely related we are.

    Some stats from my current class:
    Downs syndrome increased with age.
    Under 30 = 1 in 952 chance
    35 = 1 in 378
    40 = 1 in 106
    45 = 1 in 30
    48 = 1 in 18
  12. CinchedWaist

    CinchedWaist Elite Member

    Joined: Sep 11, 2003 Messages: 2,691 Likes Received: 1
    Other common abnormalities. The pictures for these are pretty fucked up so i don't think i will post.

    Trisomy 18 = Edwards Syndrome. due to nondisjunction in egg during meosis2. Severe mental and physical disabilities. skull often narrow and flat, low set ears. 2 outer fingers tend to overlay inner ones, fingerprints sometimes missing.

    Trisomy 13 = Patau syndrome. Low life expectancy, severe abnormalities. Sometimes born with one eye.

    Cri du Chat = missing part of chromosome 5. Crying in these individuals sounds like the crying of a cat. Impaired language developement, mental retardation and a pinched face can be features.

    Sex chromosome abnormalities are often much less severe. Some people live with them and don't even know.

    X = Turners Syndrome. Sexually underdeveloped, significant fold on neck. Cannot hear certain frequencies and cannot have children.

    XXX = Triplox. 1 in 1000 fems. Very tall, irregular periods, slightly lower intelligence.

    XXY = Klinefelters Syndrome. Underdeveloped male. Infertile, little facial hair, man breasts.

    XYY = Jacobs syndrome = 1 in 1000 males. Very tall, acne, speech and reading difficulties.
  13. Dick Quickwood

    Dick Quickwood 12oz Loyalist

    Joined: Aug 25, 2002 Messages: 14,783 Likes Received: 14
    i image searched all of those, intrestsing stuff
  14. trackstand

    trackstand Senior Member

    Joined: Jun 21, 2004 Messages: 2,262 Likes Received: 3
    "what the fuck did you just say to me?"
  15. Kr430n5_666

    Kr430n5_666 Banned

    Joined: Oct 6, 2004 Messages: 19,229 Likes Received: 30